How Coronavirus Mutates and Spreads
Coronavirus genome variations have given insight to coronavirus biology, and to the geographic spread of the virus.
Image Credit: New York Times
Covid-19 Arrived in Seattle. Where It Went From There Stunned The Scientists.
Chiu is surprised to discover that Princess Cruise and SF COVID cases likely link to original man diagnosed in Washington.
Image Credit: New York Times
CRISPR And Spit Might Be Keys To Faster, Cheaper, Easier Tests For The Coronavirus
NPR interviews Chiu about co-developing a test using CRISPR tech with a plan to eventually develop a home test kit.
Image Credit: Mammoth Biosciences
New CRISPR-Based COVID-19 Test Kit Can Diagnose Infection in Less Than an Hour
Chiu and Mammoth Biosciences submit new, accurate and faster DETECTR test for FDA approval, allowing for simpler testing.
Image Credit: NAIAD
Coronavirus: Where did ours come from? All over.
At least 8 different viral lineages found in 29 patients, suggesting multiple independent introductions of the pathogen into CA.
Image Credit: Mercury News
Coronavirus tests: researchers chase new diagnostics to fight the pandemic
Chiu stresses critical nature of fast testing and identifies CRISPR technology.
Image Credit: Nature
The man behind the sequencing of the coronavirus could have keys to the disease
Chiu’s lab is running 24 hours a day and is coming closer to characterizing the disease and test for all of California.
Image Credit: San Francisco Chronicle
Coronavirus: Tracing Grand Princess outbreak, gene detectives see link to Seattle case
Chiu discusses tracking of virus and how it travels.
Image Credit: The Mercury News
Some Patients With Wuhan Coronavirus Only Show Mild Symptoms
Charles Chiu interviewed about the relationship between symptoms and spread of coronavirus.
Image Credit: TIME
Precautions are in Place for the Wuhan Coronavirus
It seems like it was only a matter of time before the coronavirus would appear in the U.S.
Image Credit: STAT News
Your Questions Answered about the Coronavirus
Charles Chiu discusses the novel coronavirus 2019-nCoV from China on KQED radio.
Image Credit: KQED News
Passengers From Wuhan Halted From Flying To SFO Due To Coronavirus Outbreak
Charles Chiu interviewed about the identification and containment of the new coronavirus.
Image Credit: KPIX 5
San Francisco doctor testing to diagnose coronavirus
As concerns heat up about fast-spreading coronavirus from China, Chiu lab readies their sequencing tests for detecting and diagnosing the virus.
Image Credit: ABC News
UCSF Can Test for Novel Coronavirus due to Next Generation Sequencing of DNA
KCBS radio interview with Charles Chiu.
Scientists race to learn if coronavirus from China is new SARS, as first case arrives in US
Charles Chiu interviewed as an infectious diseases expert regarding the possible origins of the novel coronavirus.
Image Credit: San Francisco Chronicle
FAQ for MSSPE
This is a method for enriching of viral pathogens in metagenomic data. See FAQ: download design & analysis software, and for FAQ.
Emerging Infectious Disease Threats
UCSF Center for Next-Gen Precision Diagnostics, led by Charles Chiu, utilizes advanced genetic sequencing techniques to quickly identify new infectious threats.
Image Credit: UCSF
A Modern Tool for Diagnosing Infectious Diseases
Metagenomic sequencing is seeing increasing use in clinical laboratories.
Improving Diagnosis of Lyme Disease and other Tickborne Illnesses
Dept of Defense funds Chiu’s work to develop diagnostic tests based on multiplexed tickborne pathogen detection and Lyme disease host response.
UCSF Space Health Innovation Conference
Charles Chiu to present at the first-ever UCSF Space Health Innovation Conference on development of assays that could be run by astronauts in space.
Image Credit: Space Innovation Health Conference
Metagenomic Next-Generation Sequencing — Moving to the Clinic
Performing “deeper and deeper sequencing to, in effect, make the needle shine a bit brighter among the hay.”
Death in a Child Due to a Common Cold Virus
“We can’t really vaccinate the entire population for an extremely rare disease, which this is with respect to it causing severe illness.”
Image Credit: San Francisco Chronicle
Rapid DNA Analysis Helps Identify Mystery Diseases
“It is my hope and expectation that this powerful new diagnostic tool will transform the way that we as physicians manage infections in our critically ill patients.”
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UCSF’s Most Popular Science Stories of 2018
Charles Chiu explains why the 2018 flu season was so severe and why tickborne infections are on the rise.
Image Credit: UCSF
Machine learning to investigate polio-like illness
Researchers are probing the immune system to determine why some children develop acute flaccid myelitis.
Image Credit: Nature
Researchers still searching for answers to polio-like illness
Without that key evidence, [Chiu says], “we don’t have a smoking gun.”
Image Credit: The Globe and Mail
PromethION sequencing for diagnosis of infectious disease
Video: Chiu laboratory is harnessing the sequencing power of the PromethION to develop and validate clinical sequencing
Video Credit: Oxford Nanopore Technologies
Developing CRISPR-based Infectious Disease Diagnostics
Mammoth Biosciences has secured $23 million in Series A funds to develop new diagnostic assays based on CRISPR.
Flu Vaccine Only 15% Effective in 2017-2018
Data published from Public Health England show that the effectiveness of the flu vaccine was low in all age groups.
Image Credit: CDC
Reconstructing the Spread of Zika Virus
Zika genome sequencing using a novel Chiu lab technique tracks Zika spread in Mexico and Central America.
Lyme Disease on the Rise
Infectious disease expert Dr. Charles Chiu discusses why rates of tickborne infections have been increasing.
Image Credit: NIH
The “Canary in the Coal Mine” for Zika Virus
The marmoset model was shown to be a relevant animal model for Zika-associated pregnancy complications.
Why the Flu Season is so Bad This Year
Dr. Charles Chiu answers questions regarding the 2018 influenza season.
Image Credit: CDC
An Extra-Planetary First: NASA Sequences DNA in Space
In a scientific first, NASA has successfully performed proof-of-concept genome sequencing in space.
Image Credit: youtubify.ru
Gut Viruses Tied to Potentially Deadly Complication of Bone Marrow Transplant
In new study, certain viruses seen to raise risk of graft-versus-host disease.
Nanopore Sequencing, PCR Platforms Evaluated for Rapid Pneumonia Diagnosis in UK Study
Researchers are testing molecular diagnostics platforms to speed up diagnosis of pneumonia.
Story of Hantavirus Survivor
A Citrus Heights father questions the integrity of an inspection for hantavirus.
Next-Gen Precision Diagnostics Now Available at UCSF
A genome sequencing test is now available to help physicians diagnose mysterious cases of neurological infection.
Brain-Invading Tapeworm That Eluded Doctors Spotted by New DNA Test
Doctors diagnose neurocysticercosis using mNGS assay.
Image Credit: Getty Images
The World Is Not Ready for the Next Pandemic
Budget cuts, research gaps, and lack of pharmaceuticals leave world vulnerable to pandemics.
How to Keep the World Safe from Superbugs
Quicker diagnosis may be key to slowing antibiotic resistance.
Bay Area Research Scramble to Create Tests for Zika Virus
CDC antibody test gets emergency approval and Chiu lab develops nucleic acid test.
UCSF Scientists, Leaders Highlight Latest Advances at 2017 Precision Medicine World Conference
Scientists, clinicians and entrepreneurs shared the latest innovations in personal, predictive and preventive medicine.
A Polio-Like Virus that Paralyzes Children
More evidence for Enterovirus D68 as causative agent of paralysis.
UCSF Lab Readies Launch of Metagenomic NGS Test for Infectious Disease
Chiu lab preparing to launch a clinical mNGS-based test for meningitis and encephalitis.
Metagenomic Sleuthing Treats Illness Like a Crime Scene
Broad-spectrum infectious disease diagnosis using metagenomic sequencing.
Mysterious Paralysis-Causing Syndrome Appears to be on the Rise
The CDC is investigating a rise acute flaccid myelitis, with 50 new cases reported in 8 months.
DNA Sequenced In Space Signals Step Forward In Astronaut Medicine
Ability to sequence DNA in space could lead to improvements in astronaut health.
NASA’s DNA Sequencing in Space is a Success, UCSF Researchers Confirm
NASA collaborates with UCSF lab to sequence DNA in space.
Experts: Bay Area Unlikely to see Zika Cluster Similar to Miami
Despite Florida travel advisory, experts say little chance of Zika becoming widespread in US.
California Initiative to Advance Precision Medicine Announces Funding for 2 Projects
UCSF project to rapidly diagnose infections, UCSC project to treat pediatric cancer.
