Recent Publications

CRISPR–Cas12-based detection of SARS-CoV-2
CRISPR–Cas12-based detection of SARS-CoV-2

Broughton et al, Nature Biotechnology, April 2020

MSSPE
MSSPE (Metagenomic sequencing with spiked primer enrichment)

Deng et al, Nature Microbiology, January 2020

Clinical mNGS for Diagnosis of Meningitis and Encephalitis
Clinical mNGS for Diagnosis of Meningitis and Encephalitis

Wilson et al, New England Journal of Medicine, June 2019

Lab validation of a clinical mNGS assay for detection in cerebrospinal fluid

Miller et al, Genome Research, May 2019

Miscarriage in Zika-infected Monkeys

Dudley et al, Nature Medicine, August 2018

Establishing Causes of Acute Liver Failure

Ganger et al, American Journal of Gastroenterology, June 2018
Image Credit: CDC

CRISPR Infectious Disease Diagnostics

Chiu et al, Cell Host Microbe, June 2018

Tracking Zika Virus in the Americas

Theze et al, Cell Host Microbe, May 2018

Polyomavirus Infections of the Urologic Tract

Sirohi et al, Modern Pathology, May 2018
Image Credit: CDC

Zika Infection in Pregnant Marmosets

Seferovic et al, Scientific Reports, May 2018

Neurocysticercosis Diagnosed Using mNGS

Saporta-Keating et al, Journal of the Pediatric Infectious Diseases Society, February 2018

Metagenomic Sequencing of Transplant Respiratory Infections

Langelier et al, American Journal of Respiratory and Critical Care Medicine, February 2018

Sequencing on the International Space Station

Castro-Wallace et al, Scientific Reports, December 2017
Image Credit: NASA

Zika Infection in Marmosets Mimics the Human Illness

Chiu et al, Scientific Reports, December 2017

Pan-Viral Surveillance of Acute Liver Failure

Somasekar et al, Clinical Infectious Diseases, October 2017

mNGS Diagnosis of St. Louis Encephalitis Virus

Chiu et al, Emerging Infectious Diseases, October 2017

Metagenomic Surveillance of Ticks in California

Bouquet et al, Scientific Reports, September 2017
Image Credit: CDC

Retrovirus Upregulation in Pulmonary Hypertension

Saito et al, Circulation, September 2017

Gut Virome in Transplant Recipients

LeGoff et al, Nature Medicine, June 2017

Clinical Validation of mNGS Testing

Schlaberg et al, Archives of Pathology Lab Medicine, June 2017